35 years old female with infertility

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35 years old female visited her obstetrician/ gynecologist and complained that she was unable to get pregnant. Upon taking a medical history, the physician notes that the patient had regular 28-to-30 day cycles during the past year, during which time she had regular unprotected intercourse. She does not smoke and does not use caffeine, drugs, or alcohol. She appears to be in good health. Her ovaries and uterus appear normal in size for her age. Laboratory tests indicate that her preovulatory (late follicular phase) estradiol in 40 pg/mL (normal, 200 to 500 pg/mL) and midluteal phase progesterone is 3 ng/mL (normal, 4 to 20 ng/mL). Her husband’s sperm count is 30 million/mL.

What is the clinical indication of a fertility problem with this patient and on the clinical signs, what basic physiological principles provide insight into the infertility?

Filed Under: Discussion

Tags: 35 years old female with infertility, midluteal phase, normal count of sperm