Hepatitis A

..........................................................................................................................................................

..........................................................................................................................................................

Hepatitis A is the inflammation of the liver caused by virus , named hepatitis A virus, characterized by Jaundice and hepatomegaly . It is most common liver disease . Globally, there are an estimated 1.4 million cases of hepatitis A every year.

Causes

Hepatitis A is caused by hepatitis A virus (It is a 27 nm, positivestranded RNA, non-enveloped, cosahedral virus of the heparnavirus genus of the Picornaviridiae ). It is transmitted through faecal-oral route either by person-to-person contact or ingestion of contaminated food or water. Hepatitis A is an enteric infection spread by contaminated excreta.

Hepatatis A

 

Risk factor

  • Lack of sanitation
  • Unhygienic water
  • Drug abuser
  • living together with hepatitis A infected person

Signs and Symptoms

  • Jaundice
  • Fever
  • Loss of appetite
  • Vomiting
  • Nausea
  • Pain at abdomen
  • Clay c0lored stool
  • Dark colored urine
  • Joints pain
  • Diarrhea

Complications

  • Acute liver failure
  • Fulminant liver  failure

 Tests and Diagnosis

  • Hepatitis A is diagnosed by clinical presentation .
  • Detection of serum anti-HAV IgM antibodies
  • Liver function tests
  • Detection of HAV in stool.

 Treatment of Hepatitis A

Because acute hepatitis A is a self-limiting disease and in most cases resolves spontaneously without residual damage or squeal and no specific therapy is available, the treatment is based on symptomatic comfort , adequate  nutritional  and fluid balance and  monitoring.  Consult ur doctor before taking any drugs, supplements, which can potentially damage the liver. Alcohol should be avoided. Never used any herbal drugs because these drugs can cause more liver damage and may require liver transplantation .

Prevention

  • Drink boiled or filtered water
  • Always wash hand before and after eating
  • Personal hygiene
  • Proper disposal of Sewage
  • Wash hand after using the toilet
  • Giving Hepatitis A vaccine

Outcome(Prognosis)

It is self-limiting disease and in most cases resolves spontaneously without residual damage or sequelae . Outcome is excellent.

References:

  • mayoclinic.com
  • who.com
  • cdc.gov
  • Mauss  Berg -Rockstroh – Sarrazin – Wedemeyer (hepatology A clinical textbook, Second Edition )
  • Picture taken by news.com.au.

Leave a Reply

You must be logged in to post a comment.